Lose Weight
Bupropion
$60/mo + membership
By increasing levels of norepinephrine and dopamine in the brain, Bupropion helps to reduce appetite and cravings, leading to effective weight loss, improved mood and increased energy levels.

Suppress Emotional Eating

Enhance Metabolic Control

Premium Tier
Prescription products require an online consultation with a healthcare provider who will determine if a prescription is appropriate.
Lose Weight
- Reduces appetite and cravings
- Encourages weight loss
- Improves mood and energy levels
What is Bupropion Prescribed For?
Bupropion is an antidepressant medication that works in the brain. It is FDA-approved for the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and for smoking cessation.Clinicians prescribe it off-label to treat excess weight and obesity because clinical evidence shows it also helps people lose weight.
How Does Bupropion Work?
Bupropion is a norepinephrine-dopamine reuptake inhibitor (NDRI). It works by blocking the reuptake of norepinephrine and dopamine, which increases their levels in the brain, reducing cravings and improving mood.
What to Expect
When taking bupropion, you may experience a reduction in appetite and cravings, improved mood, and increased energy levels. Some side effects like dizziness, dry mouth, or headaches may occur but often subside as the body adjusts to the medication.
Learn More About Bupropion
Contraindications
Bupropion might not be right for you if you have certain medical conditions or take certain medication, including:
- Seizure disorder
- Anorexia or bulimia
- Recent use of monoamine oxidase inhibitors (MAOIs)
- Severe head injury
- Withdrawal from benzodiazepine or alcohol intoxication
- Pregnancy or breastfeeding
Possible Side Effects
Dizziness, Appetite suppression, Dry mouth, Nausea, Headache, Insomnia, Drowsiness, Tachycardia (irregular heartbeat), Constipation, Blurred vision, Agitation, Tremors
Warnings
BUPROPION MAY CAUSE SUICIDAL THINKING AND BEHAVIOR AND OTHER SERIOUS SIDE EFFECTS
Bupropion may cause psychiatric disorders, including suicidal thinking and behavior, hallucinations, confusion, paranoia, irrational fears and manic episodes (for people with undiagnosed bipolar disorder). The medicine could also cause high blood pressure, fast, irregular heart beats, seizures, acute angle-closure glaucoma, and death. You should not stop taking bupropion abruptly or without consulting your healthcare provider.
Warnings:
Antidepressants, including bupropion, may increase the risk of suicidal thinking and behavior in children, adolescents, and young adults.
Bupropion is not approved for use in pediatric patients.
Use with caution if you have a history of psychiatric disorders, as it may worsen pre-existing conditions.
Avoid operating heavy machinery or driving until you know how bupropion affects you.
Medical Disclaimers:
Bupropion is only FDA-approved to treat MDD, SAD, and aid in smoking cessation. Off-label use for weight loss should be discussed with a healthcare provider. Always follow the guidance of a medical professional when taking this medication.
This is a compounded product and has not been approved by the FDA. The FDA does not verify the safety or effectiveness of compounded drugs.
Explore Other Treatment Options
Real People. Real Stories.
Start with a deeper look at your health
Identifying your unique needs begins with analysis, including in-depth, 50-biomarker blood testing, personal health history, and validated questionnaires.
$60 per Biomarker Testing Kit
Any Questions?
We’ve got answers.
Getting Started
Hone is a comprehensive longevity platform that fixes symptoms and optimizes your life to increase your healthspan. Getting started is easy: purchase advanced lab diagnostics for $60, complete your testing either at-home or Labcorp, and then meet with your licensed physician for 30-45 mins.
Consult & Plan
During your 30–45 minute consult, a Hone-affiliated licensed physician will dive deep into your personal and family history, review your labs, and pinpoint the root cause of your symptoms. You’ll walk away with a personalized plan—including medications, supplements, diet, exercise, stress management, and sleep strategies—designed to relieve your symptoms and optimize your health.
During Treatment
Your treatment ships straight to your door. Since everyone metabolizes medications differently, your Hone care team stays with you every step of the way—ready to answer questions and fine-tune your plan so you feel your absolute best.
Membership & Pricing
Hone offers two memberships:
Basic – $25/month for discounted access to a limited number of medications that don’t require lab testing.
Premium – $149/month for everything Hone offers: regular lab testing, physician consults, and full access to our medications.
No commitments. Cancel anytime.