Lose Weight
Bupropion
$60/mo + membership
By increasing levels of norepinephrine and dopamine in the brain, Bupropion helps to reduce appetite and cravings, leading to effective weight loss, improved mood and increased energy levels.
Suppress Emotional Eating
Enhance Metabolic Control
Premium Tier
Prescription products require an online consultation with a healthcare provider who will determine if a prescription is appropriate.
Lose Weight
- Reduces appetite and cravings
- Encourages weight loss
- Improves mood and energy levels
What is Bupropion Prescribed For?
Bupropion is an antidepressant medication that works in the brain. It is FDA-approved for the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and for smoking cessation.Clinicians prescribe it off-label to treat excess weight and obesity because clinical evidence shows it also helps people lose weight.
How Does Bupropion Work?
Bupropion is a norepinephrine-dopamine reuptake inhibitor (NDRI). It works by blocking the reuptake of norepinephrine and dopamine, which increases their levels in the brain, reducing cravings and improving mood.
What to Expect
When taking bupropion, you may experience a reduction in appetite and cravings, improved mood, and increased energy levels. Some side effects like dizziness, dry mouth, or headaches may occur but often subside as the body adjusts to the medication.
Learn More About Bupropion
Contraindications
Bupropion might not be right for you if you have certain medical conditions or take certain medication, including:
- Seizure disorder
- Anorexia or bulimia
- Recent use of monoamine oxidase inhibitors (MAOIs)
- Severe head injury
- Withdrawal from benzodiazepine or alcohol intoxication
- Pregnancy or breastfeeding
Possible Side Effects
Dizziness, Appetite suppression, Dry mouth, Nausea, Headache, Insomnia, Drowsiness, Tachycardia (irregular heartbeat), Constipation, Blurred vision, Agitation, Tremors
Warnings
BUPROPION MAY CAUSE SUICIDAL THINKING AND BEHAVIOR AND OTHER SERIOUS SIDE EFFECTS
Bupropion may cause psychiatric disorders, including suicidal thinking and behavior, hallucinations, confusion, paranoia, irrational fears and manic episodes (for people with undiagnosed bipolar disorder). The medicine could also cause high blood pressure, fast, irregular heart beats, seizures, acute angle-closure glaucoma, and death. You should not stop taking bupropion abruptly or without consulting your healthcare provider.
Warnings:
Antidepressants, including bupropion, may increase the risk of suicidal thinking and behavior in children, adolescents, and young adults.
Bupropion is not approved for use in pediatric patients.
Use with caution if you have a history of psychiatric disorders, as it may worsen pre-existing conditions.
Avoid operating heavy machinery or driving until you know how bupropion affects you.
Medical Disclaimers:
Bupropion is only FDA-approved to treat MDD, SAD, and aid in smoking cessation. Off-label use for weight loss should be discussed with a healthcare provider. Always follow the guidance of a medical professional when taking this medication.
This is a compounded product and has not been approved by the FDA. The FDA does not verify the safety or effectiveness of compounded drugs.
Patients see an improvement in quality of life measures in 6 months such as having more energy, improved libido, and increase in strength.
Patients see their mood improve as measured by the PHQ9 (depressive symptom index) after 6 months of treatment.
Patients are still with Hone after 1 year of treatment. That's among the highest in health care.
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Hone is a comprehensive longevity platform that fixes symptoms and optimizes your life to increase your healthspan. Getting started is easy: purchase advanced lab diagnostics for $65, complete your testing either at-home or at-lab, and then meet with your licensed physician.
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During your private, telehealth consult, a Hone-affiliated licensed physician will dive deep into your personal and family history, review your labs, and pinpoint the root cause of your symptoms. You’ll walk away with a personalized plan—including medications, supplements, diet, exercise, stress management, and sleep strategies—designed to relieve your symptoms and optimize your health.
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Your treatment ships straight to your door. Since everyone metabolizes medications differently, your Hone care team stays with you every step of the way—ready to answer questions and fine-tune your plan so you feel your absolute best.
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