Education: Undergraduate: Texas A&M University-College Station, TX (B.S. Biochemistry); Medical: University of Alabama School of Medicine-Birmingham, AL (M.D.)

Expertise: Metabolism, Diabetes, and Endocrinology

Dr. Steven D. Wise is a board-certified endocrinologist with over 25 years of experience, specializing in diabetes, lipid metabolism, thyroid disorders, osteoporosis, and adrenal disorders. He is currently practicing at Houston Methodist Endocrinology Associates in Houston, Texas.

Dr. Wise earned his medical degree from the University of Alabama School of Medicine. He completed his residency in Internal Medicine at the University of Alabama Medical Center. Following his residency, Dr. Wise pursued specialized training in endocrinology, completing a fellowship in Endocrinology, Diabetes, and Metabolism at the Mayo Graduate School of Medicine.

Dr. Wise is a Fellow of the American Association of Clinical Endocrinologists (FACE). He is committed to building long-lasting relationships with his patients by listening closely and providing personalized care.

Research:

Effects of hepatic glycogen content on hepatic insulin action in humans: alteration in the relative contributions of glycogenolysis and gluconeogenesis to endogenous glucose production. Wise S, Nielsen M, Rizza R. J Clin Endocrinol Metab 1997; 82(6):1828-33.

Assessment of hepatic sensitivity to glucagon in NIDDM: use as a tool to estimate the contribution of the indirect pathway to nocturnal glycogen synthesis. Nielsen MF, Wise SD, Dinneen SF, Schwenk WF, Basu A, Rizza RA. Diabetes. 1997; 46(12):2007-16.

Dermal interstitial glucose as an indicator of ambient glycemia. Service FJ, O’Brien PC, Wise SD, Ness S, LeBlanc SM. Diabetes Care. 1997; 20(9):1426-9.

Overnight normalization of glucose concentrations improves hepatic but not extrahepatic insulin action in people with type 2 diabetes mellitus. Wise SD., Nielsen MF, Cryer PE, Rizza RA. J Clin Endocrinol Metab 1998; 83(7):2461-9.

Normal glucose-induced suppression of glucose production but impaired stimulation of glucose disposal in type 2 diabetes: evidence for a concentration-dependent defect in uptake. Nielsen MF, Basu R, Wise S, Caumo A, Cobelli C, Rizza RA. Diabetes. 1998; 47(11):1735-47.

“Practicing endocrinology is like solving a walking, talking jigsaw puzzle. It is always fascinating to find another piece that fits in a way that you never imagined, and satisfying to see the picture get more complete as you work. Every generation is tempted to believe that everything worth discovering has already been discovered. Endocrinology usually proves them wrong. There have been so many exciting discoveries in Endocrinology since I finished medical school, and I suspect that we have only the scratched the surface of how hormones are holding our bags of bones together.”