Does Creatine Cause Erectile Dysfunction?

Creatine monohydrate is one of the most well-researched and effective supplements for boosting performance, strength, muscle recovery, and brain health. Despite its proven benefits, myths about creatine—like links to hair loss and weight gain—still persist. 

One of the more egregious myths is centered around erectile dysfunction (ED). “Does creatine cause erectile dysfunction?” still pops up online, causing unnecessary confusion. The short answer: No, science doesn’t support this claim. Here’s why this myth lingers and what the research really says about creatine’s impact on your body, sexual health, and performance in bed. 

About the Expert

Paul Gittens, M.D., F.A.C.S. is a urologist specializing in the treatment of sexual health for men and women, and a specialist in female menopause and male infertility. He’s the medical director at Rockwell Centers for Sexual Medicine & Wellness in Manhattan, the Philadelphia area, and Allentown, PA.

No, Creatine Doesn’t Cause Erectile Dysfunction

The idea that creatine causes erectile dysfunction (ED) is a long-standing myth, particularly in online forums like Reddit. Its origins are hard to determine for certain, but it could be connected to concerns linking ED to chronic kidney disease and creatine’s potential strain on kidney function (1, 2). While some studies have raised alarms about high doses of creatine as it relates to kidney function, newer research has shown that healthy individuals can process it without issue (3).

“Mostly everything written on creatine shows that there are no issues with sexual function or low libido,” says urologist Paul Gittens, M.D. “I’ve done a number of literature searches on this, and I’ve not seen it,” he adds.

What does creatine do?

Creatine is a substance stored in your body—mostly in your muscles, with smaller amounts in your brain and testes. It supports the production of more adenosine triphosphate (ATP), which effectively acts as the fuel for cellular activity. Supplementing with creatine helps increase the amount of phosphocreatine in your muscles, giving you the energy boost needed to push harder during workouts (4).

For most people, creatine is safe. However, individuals with pre-existing kidney conditions should consult their doctor before use, as high doses may strain compromised kidneys. 

What causes erectile dysfunction?

ED can stem from several factors, particularly chronic conditions that affect blood vessels and nerves (5). Addressing the underlying issue can often improve erectile function, so talk to your doctor if you suspect one of these conditions is affecting your erections.

Common causes of ED include:

• Obesity
• High blood pressure
• Diabetes
• Kidney disease
• Multiple sclerosis
• Urinary tract dysfunction
• Enlarged prostate
• High cholesterol
• Low testosterone
• Metabolic syndrome
• Parkinson’s disease
• Sleep disorders (e.g., sleep apnea)

Gittens also points out that certain medications, spinal cord injuries, and psychological factors like stress, anxiety, and depression can contribute to ED. Addressing these root causes is often the most effective way to improve sexual health.

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Creatine May Indirectly Help with Erectile Dysfunction

While creatine doesn’t cause ED, it may indirectly support sexual health by enhancing overall well-being. “In general, there is a net neutral effect on sexual function and desire, and that’s shown throughout large studies,” explains Gittens. Here are the pathways through which it could do this.

Creatine can potentially boost testosterone

Creatine supplementation works through a simple feedback loop: it boosts energy production, enhancing athletic performance, which in turn leads to stronger muscles and increased testosterone levels (6). 

This cycle of muscle gain and testosterone production can improve fitness and potentially support sexual health (7). Improved cardiovascular health from regular exercise also supports erectile function by ensuring proper blood flow (8).

A small study also suggests creatine might improve sperm quality and motility, but more research is needed to fully understand its role in fertility and reproductive health (9).

Creatine supports brain health

Creatine isn’t just for improving physical performance—it can also support brain health, which can positively affect mood and reduce stress, both of which play a role in some cases of ED. Research shows that creatine boosts cognitive function, particularly memory and mental clarity, and may offer protective benefits for the brain by promoting recovery from injuries and helping prevent neurodegenerative diseases. While there’s no direct link between creatine and ED, its potential to improve brain health and mood may indirectly benefit sexual health, though more research is needed to confirm these effects.

Other Side Effects of Creatine

Creatine is generally safe for most people, but some may experience mild side effects, particularly if they take high doses. These include (10, 11):

• Dehydration: Creatine pulls water into muscle cells, so it’s important to drink plenty of fluids while supplementing. 
• Muscle cramps: Rare, but they can happen due to dehydration or electrolyte imbalances.
• Irritability: Some users report feeling a bit more irritable, though this is uncommon.

These side effects are usually manageable and can often be avoided by drinking plenty of water and following recommended dosages. But it’s still a good idea to consult your doctor before taking creatine, especially if you already have health conditions.