What Is an NAD+ Injection? How Can It Support Your Health?

If you’re looking for ways to feel your best as you age—or potentially even increase your lifespan—you’ve probably heard of NAD+. The buzzy coenzyme may slow the progression of age-related diseases, extend lifespan, and more. You can swallow NAD+ oral supplements and get NAD+ IV therapy at clinics, but the most effective way to boost your levels is with NAD injections, which you can buy online and administer in the comfort and privacy of your own home. And it’s perfectly safe.

Interested in getting NAD injections at home? Here’s everything you need to know.

About the Expert:

Candice Knight, M.D. is a board-certified Family Medicine and Integrative Medicine physician with additional certifications in Functional Medicine and Quantum Biology.

What Are NAD+ Injections

NAD injections are a form of longevity therapy that supplement the body’s production of nicotinamide adenine dinucleotide (NAD+). NAD therapy may prevent certain diseases related to aging and extend the lifespan.

“NAD+ doesn’t just boost energy—it enhances mitochondrial function, repair, and longevity by ensuring that electrons are efficiently transported into cells to make energy,” says Candice Knight, M.D. a board-certified Family Medicine and Integrative Medicine physician.

NAD+ may have only recently popped up on your radar, but researchers discovered it way back in 1906. Over the last few decades, scientists have been studying its potential to slow down or reverse age-related health issues, improve energy and focus, speed up metabolism, boost cardiovascular health, and more.

Benefits of NAD+ Injections

Studies suggest a smorgasbord of potential NAD+ benefits. Increasing NAD+ levels may have a variety of anti-aging benefits including:

• Improved muscle performance (2)
• Protection for your liver and kidneys (1)
• Improved blood vessel function (1)
• Delaying neurological diseases like Parkinson’s, Alzheimer’s, and ALS (1, 2, 3)
• Boosting immunity (1)
• Helping with weight loss (1)
• Increased lifespan (1)
• Improved brain function
• Improved athletic performance

NAD Injections vs. NAD IV Therapy

You can take NAD+ supplements or get NAD+ infusion therapy, but NAD+ injections offer some unique benefits over the other delivery methods. Among them:

Better absorption

NAD+ supplements have to travel through your digestive system before reaching your bloodstream. With injections, NAD+ is absorbed directly into your blood, so it can get to work faster (4).

Convenience

NAD+ IV drips also bypass the gut, but you can’t DIY an IV. You need to spend several hours at a clinic, tethered to an IV drip to get a similar dose to home injections. 

NAD+

NAD+ vs. NADH—What’s the Difference?

What is NAD+ (NAD Plus) and Why Is it Important?

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How Much Do NAD Injections Cost?

NAD+ infusion therapy sessions can run upwards of $1200 per session, and NAD+ injections for home use can cost $425 per month or more through other companies.

NAD+ injections through Hone are just $165 per month. 

You’ll also pay a monthly membership fee, which varies depending on whether or not you are receiving testosterone therapy. If you only take NAD+, your monthly membership fee is $25. If you’re on TRT as well and require periodic lab testing, the monthly membership fee is $129.

Are NAD+ Injections Safe?

NAD+ injections are safe when they are provided as a prescription and administered with the correct dosage. “NAD+ injections are bioidentical to the NAD+ naturally produced in the body. NAD+ does not accumulate in the body (no known toxic dose) and has been clinically used for decades for neurological health, energy metabolism, and addiction recovery,” adds Knight.

Buying NAD+ injections online—or frankly, buying any supplement on the internet—isn’t something to take lightly. The Food and Drug Administration doesn’t regulate supplements the same way they regulate medications, so it’s important to get supplements, including NAD injections from a source you can trust.

You will also need a prescription to safely receive NAD+ injections. Schedule an appointment with our licensed medical professionals to determine if a prescription is appropriate.

Also consider the following side effects of NAD+ injections:

• Fatigue or lethargy (5)
• Nausea or stomach discomfort (6)
• Flushing or warmth (7)
• Headache (7)
• Mild dizziness (especially in those with low blood pressure)
• Metabolic disorders like decreased insulin sensitivity (5)
• Liver toxicity (7)
• Temporary histamine reactions (mild allergy-like symptoms) in sensitive individuals