Ezetimibe
$37/mo + membership
Ezetimibe helps lower cholesterol by reducing how much is absorbed in the gut before it ever reaches the bloodstream. By limiting this upstream source of cholesterol, it supports long-term heart health and lowers cardiovascular risk. Unlike statins, which work in the liver, ezetimibe targets cholesterol at the point of absorption. This makes it a flexible, prevention-focused option within a modern heart-health strategy.
Lowers Cholesterol Absorption
Once-daily Oral Medication
Premium Tier
Prescription products require an online consultation with a healthcare provider who will determine if a prescription is appropriate.
Improve Cardiovascular Health
- May increase cholesterol support
- May increase energy
- May reduce arterial build up
- May reduce vascular stress
What Is Ezetimibe Prescribed For?
Ezetimibe is a prescription medication used to lower LDL cholesterol and other harmful cholesterol particles by reducing how much cholesterol is absorbed from the digestive tract.
In preventative heart care ezetimibe is commonly used for people who:
- Need additional LDL or ApoB reduction
- Prefer a non-statin or statin-sparing approach
- Are building a comprehensive, long-term heart health plan
By lowering the number of cholesterol-carrying particles in the blood, ezetimibe helps reduce the buildup that can damage arteries over time.
How Does Ezetimibe Work?
Ezetimibe blocks a protein in the small intestine that normally helps cholesterol move into the bloodstream.
By reducing the absorption of both dietary and biliary cholesterol, ezetimibe:
- Lowers LDL cholesterol
- Reduces ApoB-containing cholesterol particles
- Decreases the overall cholesterol burden in circulation
Because it works through absorption rather than production, ezetimibe can be used on its own or alongside other cholesterol-lowering therapies.
Who Is Ezetimibe Right For?
Ezetimibe may be an appropriate form of cardiovascular care for people who want to proactively manage cholesterol and improve long-term health outcomes.
It’s often considered for people who:
- Have elevated LDL-C or ApoB despite lifestyle optimization
- Want additional cholesterol lowering without higher statin doses
- Don’t tolerate statins well or prefer a non-statin option
- Have a family history of cardiovascular disease
- Are focused on long-term prevention rather than reactive care
Ezetimibe fits naturally into Hone’s preventive approach by addressing cholesterol-driven risk early, before lasting damage occurs.
Learn More About Ezetimibe
Benefits
Ezetimibe offers a precise, prevention-focused approach to cholesterol management, helping reduce heart risk without overburdening the body.
- Lowers LDL cholesterol and ApoB particle levels
- Reduces cholesterol absorption at the source
- Can be used alone or with other lipid therapies
- Minimal systemic exposure
- Well tolerated with once-daily oral dosing
- Supports long-term cardiovascular risk reduction
Contraindications
Ezetimibe may not be appropriate for if you:
- Have active liver disease or persistently abnormal liver tests
- Have a sensitivity or allergy to ezetimibe
- Are pregnant or breastfeeding
Final eligibility is determined by a licensed healthcare provider.
Possible Side Effects
Ezetimibe is generally well tolerated. Possible side effects may include:
- Gastrointestinal discomfort
- Fatigue
- Headache
- Muscle aches (rare, more common when combined with statins)
- Mild elevations in liver enzymes
Most side effects are uncommon and typically mild.
Warnings
- Liver function monitoring may be recommended, especially when combined with other cholesterol-lowering medications.
- Share all medications and supplements with your provider before starting treatment
- Report any unexplained muscle symptoms promptly
Always follow your provider’s guidance and monitoring recommendations.
Patients see an improvement in quality of life measures in 6 months such as having more energy, improved libido, and increase in strength.
Patients see their mood improve as measured by the PHQ9 (depressive symptom index) after 6 months of treatment.
Patients are still with Hone after 1 year of treatment. That's among the highest in health care.
Get Your Consultation for Medications
Biomarker Test
Optimal Health Biomarker Test
- 50+ biomarkers
- Test at 2,000+ lab locations
- FSA/HSA eligible
$165 $65
Physician Consultation
- Private 1:1 video consultation
- Board-certified experts
Included
Personalized Treatment Plan
- Comprehensive test results
- Biomarker breakdown
- Tailored prescriptions
Included
Real People. Real Stories.
* Compensated Hone Patient
Start with a deeper look at your health
Identifying your unique needs begins with analysis, including in-depth, 50-biomarker blood testing, personal health history, and validated questionnaires.
$65 per Biomarker Test
Any Questions?
We’ve got answers.
Getting Started
Hone is a comprehensive longevity platform that fixes symptoms and optimizes your life to increase your healthspan. Getting started is easy: purchase advanced lab diagnostics for $65, complete your testing either at-home or at-lab, and then meet with your licensed physician.
Consult & Plan
During your private, telehealth consult, a Hone-affiliated licensed physician will dive deep into your personal and family history, review your labs, and pinpoint the root cause of your symptoms. You’ll walk away with a personalized plan—including medications, supplements, diet, exercise, stress management, and sleep strategies—designed to relieve your symptoms and optimize your health.
During Treatment
Your treatment ships straight to your door. Since everyone metabolizes medications differently, your Hone care team stays with you every step of the way—ready to answer questions and fine-tune your plan so you feel your absolute best.
Membership & Pricing
Hone offers two memberships:
Basic – $25/month for advanced lab testing every 6 months, the ability to purchase physician consults, and members-only pricing on select medications and supplements.
Premium – $155/month for everything Hone offers: regular lab testing, physician consults, and full access to our medications.
No commitments. Cancel anytime.