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Vitamin B12

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Vitamin B12 is essential for red blood cell formation and DNA production. Treating a B12 deficiency may boost energy and mood, reduce stress and fatigue, and decrease symptoms of multiple conditions.

  • May improve mood

  • May support central nervous system

  • May reduce risk of vision loss

  • May reduce risk of cognitive decline

  • Treats pernicious anemia

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Prescription products require an online consultation with a healthcare provider who will determine if a prescription is appropriate.

What is Vitamin B12 Prescribed For? How Does Vitamin B12 Work? What to Expect

Vitamin B12 is one of the most important essential vitamins for health and is an important coenzyme that is required by every cell in your body. Vitamin B12 is needed for red blood cell formation and DNA production, and supplementation may help with anemia, fatigue, low energy, immunity, detoxification, nerve problems, pain, mental health, insomnia, chronic illnesses, and more. Since it’s not made in the body, it has to come from an external source via diet and/or supplementation.

In the United States, 3-6% of the population are vitamin B12 deficient and 15-20% have marginally depleted levels (source).

Vitamin B12 plays a crucial role in numerous cellular processes, most notably in the formation of new blood cells and the maintenance of neurological health. On a cellular level, B12 serves as an essential cofactor for two key enzymatic reactions involving methionine synthase and methylmalonyl-CoA mutase.

Methionine synthase facilitates the conversion of homocysteine into methionine, which is vital for producing various molecules, including phospholipids and neurotransmitters, as well as for regulating gene expression. A deficiency in B12 can lead to megaloblastic anemia. Meanwhile, methylmalonyl-CoA mutase is crucial for breaking down odd-chain fatty acids and branched-chain amino acids. A shortage of B12 results in the accumulation of methylmalonyl-CoA, which can cause the neurological issues associated with vitamin B12 deficiency.

The time it takes to feel less tired after a B12 injection can vary. Some people report feeling more energetic within a few days, while others might not notice improvements for several weeks, depending on the level of deficiency.

Effects from a B12 injection can last several weeks to months, depending on your absorption rate, metabolism, and severity of B12 deficiency.

Vitamin B12

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Contraindications

Tell your provider about your other medicines, especially: chloramphenicol, colchicine, antibiotics, metformin, or medicines that reduce stomach acid, such as cimetidine (Tagamet), omeprazole (Prilosec), lansoprazole (Prevacid), esomeprazole (Nexium), and ranitidine (Zantac).

 

 

Possible Side Effects

Potential side effects include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Fatigue
  • Weakness
  • Loss of appetite
  • A tingling sensation in the feet or hands
  • Redness, swelling, or bruising at the injection site

In the event you feel you are in imminent danger or have signs of an allergic reaction, you should contact emergency services immediately. For general symptoms, please advise your provider.

Warnings

Vitamin B12 (Methylcobalamin) comes as a liquid and is injected intramuscularly. Your dosage will be based on your medical condition, response to treatment, and other medications you’re taking. Please take it as advised by your provider.

Vitamin B12 should not be taken by children, pets, those who are pregnant or breastfeeding, or those who are allergic to any of the ingredients in vitamin B12 (Methylcobalamin). Avoid drinking large amounts of alcohol while using vitamin B12.

Make sure your health care provider knows if you have: Leber’s Disease, benzyl alcohol hypersensitivity or allergy, hypokalemia, cobalt allergy, post-surgical stent placement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Multiple third-party studies have shown the health benefits of B12. While many of the studies used animal models and have not been proven in humans yet, clinical trials are ongoing.

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