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Low Energy Hot Flashes Inflammation Cognition TRT Brain Fog

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B12 Injections

$60/mo + membership

Vitamin B12 is essential for red blood cell formation and DNA production. Treating a deficiency with B12 injections may boost energy and mood, reduce stress and fatigue, and decrease symptoms of multiple conditions.

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Aid Nervous System Health

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  • May improve mood
  • May support central nervous system
  • May reduce risk of vision loss
  • May reduce risk of cognitive decline
  • Treats pernicious anemia

What is Vitamin B-12 prescribed for?

Vitamin B12 is one of the most important essential vitamins for health and is an important coenzyme that is required by every cell in your body. Vitamin B12 is needed for red blood cell formation and DNA production, and supplementation may help with anemia, fatigue, low energy, immunity, detoxification, nerve problems, pain, mental health, insomnia, chronic illnesses, and more. Since it’s not made in the body, it has to come from an external source via diet and/or supplementation.

In the United States, 3-6% of the population are vitamin B12 deficient and 15-20% have marginally depleted levels.

How does Vitamin B-12 work?

Vitamin B12 plays a crucial role in numerous cellular processes, most notably in the formation of new blood cells and the maintenance of neurological health. On a cellular level, B12 serves as an essential cofactor for two key enzymatic reactions involving methionine synthase and methylmalonyl-CoA mutase.

Methionine synthase facilitates the conversion of homocysteine into methionine, which is vital for producing various molecules, including phospholipids and neurotransmitters, as well as for regulating gene expression. A deficiency in B12 can lead to megaloblastic anemia. Meanwhile, methylmalonyl-CoA mutase is crucial for breaking down odd-chain fatty acids and branched-chain amino acids. A shortage of B12 results in the accumulation of methylmalonyl-CoA, which can cause the neurological issues associated with vitamin B12 deficiency.

What to expect after use.

The time it takes to feel less tired after a B12 injection can vary. Some people report feeling more energetic within a few days, while others might not notice improvements for several weeks, depending on the level of deficiency.

Effects from a B12 injection can last several weeks to months, depending on your absorption rate, metabolism, and severity of B12 deficiency.

Learn More About Vitamin B-12

Contraindications

Tell your provider about your other medicines, especially: chloramphenicol, colchicine, antibiotics, metformin, or medicines that reduce stomach acid, such as cimetidine (Tagamet), omeprazole (Prilosec), lansoprazole (Prevacid), esomeprazole (Nexium), and ranitidine (Zantac).

Possible Side Effects

Potential side effects include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Fatigue
  • Weakness
  • Loss of appetite
  • A tingling sensation in the feet or hands
  • Redness, swelling, or bruising at the injection site

In the event you feel you are in imminent danger or have signs of an allergic reaction, you should contact emergency services immediately. For general symptoms, please advise your provider.

Warnings

Vitamin B12 (Methylcobalamin) comes as a liquid and is injected intramuscularly. Your dosage will be based on your medical condition, response to treatment, and other medications you’re taking. Please take it as advised by your provider.

Vitamin B12 should not be taken by children, pets, those who are pregnant or breastfeeding, or those who are allergic to any of the ingredients in vitamin B12 (Methylcobalamin). Avoid drinking large amounts of alcohol while using vitamin B12.

Make sure your health care provider knows if you have: Leber’s Disease, benzyl alcohol hypersensitivity or allergy, hypokalemia, cobalt allergy, post-surgical stent placement

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Real People. Real Stories.

Story No. 444

I'd say the biggest impacts have been the consistency in my energy levels throughout the day.

Jarred, 42
Compensated Hone Patient

Story No. 111

With Hone, I was able to get first class care from a doctor I chose. She was informed about the intersection of chronic illness and reproductive health, and had a plan made up for me quickly that addressed all my concerns.

Shannon, 38
Compensated Hone Patient

Story No. 194

Very comprehensive review of my blood test and results along with some very helpful suggestions on things I needed to do to address some of the numbers. Didn’t try to sell me on anything, just honest diagnosis.

Josh, 37
Compensated Hone Patient

Story No. 132

I have definitely have improved energy, I have less overall pain, and then of course, sexually, it's been good.

Dom, 41
Compensated Hone Patient

Story No. 1947

The benefits have been more than just physical- I 'feel' better in my head. I am clearer and feel confident about myself beyond appearance.

Dustin, 52
Compensated Hone Patient

Story No. 732

I feel really well supported by the Hone doctor, and my problem of fatigue was solved almost within two weeks of meeting with her.

Polly, 44
Compensated Hone Patient

Story No. 444

I'd say the biggest impacts have been the consistency in my energy levels throughout the day.

Jarred, 42
Compensated Hone Patient

Story No. 111

With Hone, I was able to get first class care from a doctor I chose. She was informed about the intersection of chronic illness and reproductive health, and had a plan made up for me quickly that addressed all my concerns.

Shannon, 38
Compensated Hone Patient

Story No. 194

Very comprehensive review of my blood test and results along with some very helpful suggestions on things I needed to do to address some of the numbers. Didn’t try to sell me on anything, just honest diagnosis.

Josh, 37
Compensated Hone Patient

Story No. 132

I have definitely have improved energy, I have less overall pain, and then of course, sexually, it's been good.

Dom, 41
Compensated Hone Patient

Story No. 1947

The benefits have been more than just physical- I 'feel' better in my head. I am clearer and feel confident about myself beyond appearance.

Dustin, 52
Compensated Hone Patient

Story No. 732

I feel really well supported by the Hone doctor, and my problem of fatigue was solved almost within two weeks of meeting with her.

Polly, 44
Compensated Hone Patient

Start with a deeper look at your health

Identifying your unique needs begins with analysis, including in-depth, 50-biomarker blood testing, personal health history, and validated questionnaires.

$60 per Biomarker Test

Low Energy Hot Flashes Inflammation Cognition TRT Brain Fog

Any Questions?
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Getting Started

Hone is  a comprehensive longevity platform that fixes symptoms and optimizes your life to increase your healthspan. Getting started is easy: purchase advanced lab diagnostics for $60, complete your testing either at-home or Labcorp, and then meet with your licensed physician for 30-45 mins.

Consult & Plan

During your 30–45 minute consult, a Hone-affiliated licensed physician will dive deep into your personal and family history, review your labs, and pinpoint the root cause of your symptoms. You’ll walk away with a personalized plan—including medications, supplements, diet, exercise, stress management, and sleep strategies—designed to relieve your symptoms and optimize your health.

During Treatment

Your treatment ships straight to your door. Since everyone metabolizes medications differently, your Hone care team stays with you every step of the way—ready to answer questions and fine-tune your plan so you feel your absolute best.

Membership & Pricing

Hone offers two memberships:

Basic – $25/month for discounted access to a limited number of medications that don’t require lab testing.

Premium – $149/month for everything Hone offers: regular lab testing, physician consults, and full access to our medications.

No commitments. Cancel anytime.