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Low Energy Hot Flashes Inflammation Cognition TRT Brain Fog

Live Longer & Better

Low Dose Naltrexone

$38/mo + membership

Low-dose naltrexone (LDN) rebalances immune function and calms chronic inflammation. It boosts endorphin activity, lifts mood, sharpens focus, and restores steady energy so your body can operate at its best.

Balance Hormones

Oral Medication

Premium Tier

Start with a deeper look

Prescription products require an online consultation with a healthcare provider who will determine if a prescription is appropriate.

Live Longer & Better

  • Reduces chronic pain and inflammation
  • Helps to balance over-reacting autoimmune disease
  • Boosts natural endorphins, which helps stabilize mood by lowering anxiety and irritability
  • Enhances metabolism, energy and reduces fatigue
  • Promotes restorative sleep
  • May support thyroid and metabolic health
  • May aid in hormone balance and reproductive health

What is Low Dose Naltrexone Prescribed For?

Low-dose naltrexone (LDN) helps regulate immune activity and reduce chronic inflammation. It’s commonly prescribed for autoimmune and inflammatory conditions, including thyroid disorders, arthritis, and chronic pain syndromes.

How Does Low Dose Naltrexone Work?

At low doses, naltrexone briefly blocks opioid receptors, prompting the body to release endorphins and enkephalins—natural chemicals that regulate pain, mood, and immune activity. This short rebound effect reduces inflammation and supports more balanced immune function over time.

Who is Low Dose Naltrexone Right For?

Low-dose naltrexone prescriptions are designed for individuals with inflammation-driven conditions—such as autoimmune disorders, chronic pain, or fatigue. Patients interested in buying LDN want to ease symptoms and restore balance without harsh immune suppression. It supports steadier energy, sharper focus, and better overall resilience.

Learn More About Low Dose Naltrexone

Contraindications

  • Current opioid use
  • Liver failure
  • Pregnancy/breastfeeding
  • Organ transplant recipients

Possible Side Effects

  • Sleep disturbances / vivid dreams
  • Headache
  • GI upset / nausea
  • Fatigue
  • Anxiety or irritability

Warnings

Consult with your physician as this prescription may have reactions with other medications.

This is a compounded product and has not been approved by the FDA. The FDA does not verify the safety or effectiveness of compounded drugs.

0%

Patients see an improvement in quality of life measures in 6 months such as having more energy, improved libido, and increase in strength.

0%

Patients see their mood improve as measured by the PHQ9 (depressive symptom index) after 6 months of treatment.

0%

Patients are still with Hone after 1 year of treatment. That's among the highest in health care.

Get Your Consultation for Medications

Get our biomarker test and create a customized health plan with your wholistic health goals in mind.

Biomarker Test

(8901)
Includes:

Optimal Health Biomarker Test

  • 40+ biomarkers
  • Test at 2,000+ lab locations
  • FSA/HSA eligible

$165 $65

Physician Consultation

  • 45-min private video consultation
  • Board-certified experts

Included

Personalized Treatment Plan

  • Comprehensive test results
  • Biomarker breakdown
  • Tailored prescriptions

Included

Subtotal: $165 $65
Get Started Now

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Real People. Real Stories.

Story No. 444

Jarred, 42*

I'd say the biggest impacts have been the consistency in my energy levels throughout the day.

Story No. 111

Shannon, 38*

With Hone, I was able to get first class care from a doctor I chose. She was informed about the intersection of chronic illness and reproductive health, and had a plan made up for me quickly that addressed all my concerns.

Story No. 194

Josh, 37*

Very comprehensive review of my blood test and results along with some very helpful suggestions on things I needed to do to address some of the numbers. Didn’t try to sell me on anything, just honest diagnosis.

Story No. 132

Dom, 41*

I have definitely have improved energy, I have less overall pain, and then of course, sexually, it's been good.

Story No. 1947

Dustin, 52*

The benefits have been more than just physical- I 'feel' better in my head. I am clearer and feel confident about myself beyond appearance.

Story No. 732

Polly, 44*

I feel really well supported by the Hone doctor, and my problem of fatigue was solved almost within two weeks of meeting with her.

Story No. 444

Jarred, 42*

I'd say the biggest impacts have been the consistency in my energy levels throughout the day.

Story No. 111

Shannon, 38*

With Hone, I was able to get first class care from a doctor I chose. She was informed about the intersection of chronic illness and reproductive health, and had a plan made up for me quickly that addressed all my concerns.

Story No. 194

Josh, 37*

Very comprehensive review of my blood test and results along with some very helpful suggestions on things I needed to do to address some of the numbers. Didn’t try to sell me on anything, just honest diagnosis.

Story No. 132

Dom, 41*

I have definitely have improved energy, I have less overall pain, and then of course, sexually, it's been good.

Story No. 1947

Dustin, 52*

The benefits have been more than just physical- I 'feel' better in my head. I am clearer and feel confident about myself beyond appearance.

Story No. 732

Polly, 44*

I feel really well supported by the Hone doctor, and my problem of fatigue was solved almost within two weeks of meeting with her.

* Compensated Hone Patient

Start with a deeper look at your health

Identifying your unique needs begins with analysis, including in-depth, 50-biomarker blood testing, personal health history, and validated questionnaires.

$65 per Biomarker Test

Get Started
Low Energy Hot Flashes Inflammation Cognition TRT Brain Fog

Any Questions?
We’ve got answers.

Getting Started

Hone is  a comprehensive longevity platform that fixes symptoms and optimizes your life to increase your healthspan. Getting started is easy: purchase advanced lab diagnostics for $65, complete your testing either at-home or at-lab, and then meet with your licensed physician for 30-45 mins.

Consult & Plan

During your 30–45 minute consult, a Hone-affiliated licensed physician will dive deep into your personal and family history, review your labs, and pinpoint the root cause of your symptoms. You’ll walk away with a personalized plan—including medications, supplements, diet, exercise, stress management, and sleep strategies—designed to relieve your symptoms and optimize your health.

During Treatment

Your treatment ships straight to your door. Since everyone metabolizes medications differently, your Hone care team stays with you every step of the way—ready to answer questions and fine-tune your plan so you feel your absolute best.

Membership & Pricing

Hone offers two memberships:

Basic – $25/month for advanced lab testing every 6 months, the ability to purchase physician consults, and members-only pricing on select medications and supplements.

Premium – $149/month for everything Hone offers: regular lab testing, physician consults, and full access to our medications.

No commitments. Cancel anytime.

Uncover what's possible with Hone.

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