Bi-est cream
$80/mo + membership
Hone’s Bi-est Cream is available as a 50/50 or 80/20 compound of estradiol and estriol, and is used as a topical treatment to balance hormones and alleviate menopausal symptoms like hot flashes and night sweats.
Balance Estradiol & Estriol
Target Vaginal Dryness
Premium Tier
Prescription products require an online consultation with a healthcare provider who will determine if a prescription is appropriate.
Relieve Menopause Symptoms
- Promotes healthy natural estrogen levels
- Improves hot flashes and night sweats
- Supports bone health
- May benefit urinary tract health
What is Bi-est Cream Prescribed For?
Bi-est cream is a topical hormone therapy combining two natural estrogens, estradiol and estriol, used to balance hormones and alleviate menopausal symptoms. Naturally derived from soy, bi-est cream supports women with hot flashes, night sweats, and menopause-related UTIs.
How Does Bi-est Cream Work?
Bi-est cream offers superior absorption by combining estradiol and estriol, identical to those found in the body. Applied to the skin, it is hypoallergenic and non-greasy. Bi-est cream helps balance hormones and provides relief from menopausal symptoms such as hot flashes.
What to Expect
Bi-est cream may provide relief from menopausal symptoms such as hot flashes and improved hormone balance in anywhere from one to six months.
Learn More About Bi-est Cream
Contraindications
Bi-est cream might not be right for you if you have certain medical conditions, including:
- Known anaphylactic reaction or angioedema to estradiol or other components
- Known liver dysfunction or disease
- Active blood clot or a history of blood clots
- Liver dysfunction
- Pregnancy
Possible Side Effects
Possible side effects include: Weight gain, Fatigue, Skin changes like acne, Changes in facial hair, Bloating, cramping, spotting, Mood swings, irritability, Headaches, Breast tenderness
Warnings
For external cosmetic use only. If pregnant or nursing, consult a healthcare professional before using this product. Cease using this product and seek medical attention if skin irritation or other negative reactions occur. Do not use if tamper-evident seal is broken or missing.
California Prop 65 Law requires this statement: This product contains estrogen, a chemical known only to the state of California to cause cancer.
KEEP OUT OF REACH OF CHILDREN.
Patients see an improvement in quality of life measures in 6 months such as having more energy, improved libido, and increase in strength.
Patients see their mood improve as measured by the PHQ9 (depressive symptom index) after 6 months of treatment.
Patients are still with Hone after 1 year of treatment. That's among the highest in health care.
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