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Relieve Menopause Symptoms

Transdermal Estradiol Patch

$58/mo + membership

Estradiol patches can help alleviate symptoms of menopause, including hot flashes, vaginal dryness, and osteoporosis, by supplementing reduced estrogen levels.

Steady Estrogen Delivery

Relieve Menopausal Symptoms

Premium Tier

Relieve Menopause Symptoms

  • Improves hot flashes and night sweats
  • Supports bone health
  • Stabilizes mood

What are Transdermal Estradiol Patches Prescribed For?

Estradiol (in either transdermal gel, patch, or spray forms) is utilized for managing moderate to severe menopausal symptoms. Additionally, it addresses vaginal changes such as dryness, itching, and burning due to low estrogen levels. This medication is further employed in premenopausal women with insufficient estrogen production and in postmenopausal women to prevent osteoporosis.

How Do Estrogen Patches Work?

Transdermal estradiol patches are used to alleviate menopausal symptoms by supplementing the estrogen women’s bodies lose with aging. It treats moderate to severe hot flashes, night sweats, and mood swings. It improves vaginal dryness, itching, and burning.

What to Expect

When using the transdermal estradiol patch, you can expect a reduction in menopausal symptoms such as hot flashes and night sweats within a few weeks. Vaginal symptoms like dryness and itching should also improve. Consistent use helps maintain bone density, reducing the risk of osteoporosis. Regular follow-ups with your healthcare provider are essential to monitor your progress and adjust the dosage if necessary​.

Learn More About Transdermal Estradiol Patch

Contraindications

Transdermal estradiol patches might not be right for you if you have certain medical conditions, including:

  • Undiagnosed vaginal bleeding
  • Breast or estrogen-dependent cancers
  • Active or historical blood clots
  • Liver issues
  • Known or suspected pregnancy

Possible Side Effects

  • Vaginal yeast infections, itching, back pain, and diarrhea
  • Vaginal irritation from the applicator, trouble sleeping, and depression
  • Allergic reactions, heart attack, stroke, blood clots, breast lumps, and unusual vaginal bleeding

Warnings

  • Increased risk of endometrial cancer
  • Increased risk of cardiovascular disorders
  • Increased risk of probable dementia in postmenopausal women
  • Increased risk of breast cancer
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Patients see an improvement in quality of life measures in 6 months such as having more energy, improved libido, and increase in strength.

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Patients see their mood improve as measured by the PHQ9 (depressive symptom index) after 6 months of treatment.

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Patients are still with Hone after 1 year of treatment. That's among the highest in health care.

Get Your Consultation for Medications

Get our biomarker test and create a customized health plan with your wholistic health goals in mind.

Biomarker Test

Includes:

Optimal Health Biomarker Test

  • 40+ biomarkers
  • Test at 2,000+ lab locations
  • FSA/HSA eligible

$165 $65

Physician Consultation

  • 45-min private video consultation
  • Board-certified experts

Included

Personalized Treatment Plan

  • Comprehensive test results
  • Biomarker breakdown
  • Tailored prescriptions

Included

Subtotal: $165 $65

Explore Other Treatment Options

Relieve Menopause Symptoms

Testosterone (Cream)

Topical testosterone cream is a treatment option for symptoms related to menopause and testosterone deficiency, and can help to overcome decreased libido, fatigue and mood changes.

Relieve Menopause Symptoms

Testosterone (Injections)

In women, testosterone injections are intended to help with symptoms of menopause such as decreased libido, bone loss, and irregular periods.

Relieve Menopause Symptoms

Bi-est cream

Hone’s Bi-est Cream is available as a 50/50 or 80/20 compound of estradiol and estriol, and is used as a topical treatment to balance hormones and alleviate menopausal symptoms like hot flashes and night sweats.

Relieve Menopause Symptoms

Progesterone

Prescription progesterone tablets help balance and regulate the body’s natural hormone levels to benefit women undergoing menopause or experiencing menstrual conditions.

Relieve Menopause Symptoms

Estrace® Estradiol Cream

Delivering estradiol in the form of a vaginal cream, Estrace® effectively alleviates menopause symptoms like vaginal dryness and urinary tract infections while supporting overall vaginal health.

Testosterone (Cream)
Testosterone
Bi-est cream
Progesterone
Estradiol Cream

Real People. Real Stories.

Story No. 444

Jarred, 42*

I'd say the biggest impacts have been the consistency in my energy levels throughout the day.

Story No. 111

Shannon, 38*

With Hone, I was able to get first class care from a doctor I chose. She was informed about the intersection of chronic illness and reproductive health, and had a plan made up for me quickly that addressed all my concerns.

Story No. 194

Josh, 37*

Very comprehensive review of my blood test and results along with some very helpful suggestions on things I needed to do to address some of the numbers. Didn’t try to sell me on anything, just honest diagnosis.

Story No. 132

Dom, 41*

I have definitely have improved energy, I have less overall pain, and then of course, sexually, it's been good.

Story No. 1947

Dustin, 52*

The benefits have been more than just physical- I 'feel' better in my head. I am clearer and feel confident about myself beyond appearance.

Story No. 732

Polly, 44*

I feel really well supported by the Hone doctor, and my problem of fatigue was solved almost within two weeks of meeting with her.

Story No. 444

Jarred, 42*

I'd say the biggest impacts have been the consistency in my energy levels throughout the day.

Story No. 111

Shannon, 38*

With Hone, I was able to get first class care from a doctor I chose. She was informed about the intersection of chronic illness and reproductive health, and had a plan made up for me quickly that addressed all my concerns.

Story No. 194

Josh, 37*

Very comprehensive review of my blood test and results along with some very helpful suggestions on things I needed to do to address some of the numbers. Didn’t try to sell me on anything, just honest diagnosis.

Story No. 132

Dom, 41*

I have definitely have improved energy, I have less overall pain, and then of course, sexually, it's been good.

Story No. 1947

Dustin, 52*

The benefits have been more than just physical- I 'feel' better in my head. I am clearer and feel confident about myself beyond appearance.

Story No. 732

Polly, 44*

I feel really well supported by the Hone doctor, and my problem of fatigue was solved almost within two weeks of meeting with her.

* Compensated Hone Patient

Start with a deeper look at your health

Identifying your unique needs begins with analysis, including in-depth, 50-biomarker blood testing, personal health history, and validated questionnaires.

$65 per Biomarker Test

Low Energy Hot Flashes Inflammation Cognition TRT Brain Fog

Any Questions?
We’ve got answers.

Getting Started

Hone is  a comprehensive longevity platform that fixes symptoms and optimizes your life to increase your healthspan. Getting started is easy: purchase advanced lab diagnostics for $65, complete your testing either at-home or at-lab, and then meet with your licensed physician for 30-45 mins.

Consult & Plan

During your 30–45 minute consult, a Hone-affiliated licensed physician will dive deep into your personal and family history, review your labs, and pinpoint the root cause of your symptoms. You’ll walk away with a personalized plan—including medications, supplements, diet, exercise, stress management, and sleep strategies—designed to relieve your symptoms and optimize your health.

During Treatment

Your treatment ships straight to your door. Since everyone metabolizes medications differently, your Hone care team stays with you every step of the way—ready to answer questions and fine-tune your plan so you feel your absolute best.

Membership & Pricing

Hone offers two memberships:

Basic – $25/month for discounted access to a limited number of medications that don’t require lab testing.

Premium – $149/month for everything Hone offers: regular lab testing, physician consults, and full access to our medications.

No commitments. Cancel anytime.