Relieve Menopause Symptoms
Estrace® Estradiol Cream
$40/mo + membership
Delivering estradiol in the form of a vaginal cream, Estrace® effectively alleviates menopause symptoms like vaginal dryness and urinary tract infections while supporting overall vaginal health.

Restore Vaginal Health

Relieve Dryness and Discomfort

Premium Tier
Prescription products require an online consultation with a healthcare provider who will determine if a prescription is appropriate.
Relieve Menopause Symptoms
- Improves metabolism
- Enhances cognitive function
- Improves metabolic rate
- Enhances mental clarity
- Improves mood
- May reduce risk of osteoporosis
What is Estrace® Estradiol Cream Prescribed For?
Women are prescribed estradiol vaginal cream to help reduce menopause symptoms such as vaginal dryness and urinary tract infections. The hormones in estradiol cream support overall vaginal health.
How Does Estadiol Cream Work?
Gently insert the applicator into your vagina and press the plunger downward to release the cream.
What to Expect
Vaginal estrogen is used to treat vaginal dryness, itching, and burning; painful or difficult urination; and sudden need to urinate immediately in women who are experiencing or have experienced menopause (change of life; the end of monthly menstrual periods).
Learn More About Estrace® Estradiol Cream
Contraindications
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital.
Possible Side Effects
Application site irritation, Breast tenderness, Nausea, Headache, Mood changes
Warnings
Consult with your physician as this prescription may have reactions with other medications.
Explore Treatment Options
Real People. Real Stories.
Start with a deeper look at your health
Identifying your unique needs begins with analysis, including in-depth, 50-biomarker blood testing, personal health history, and validated questionnaires.
$60 per Biomarker Testing Kit
Any Questions?
We’ve got answers.
Getting Started
Hone is a comprehensive longevity platform that fixes symptoms and optimizes your life to increase your healthspan. Getting started is easy: purchase advanced lab diagnostics for $60, complete your testing either at-home or Labcorp, and then meet with your licensed physician for 30-45 mins.
Consult & Plan
During your 30–45 minute consult, a Hone-affiliated licensed physician will dive deep into your personal and family history, review your labs, and pinpoint the root cause of your symptoms. You’ll walk away with a personalized plan—including medications, supplements, diet, exercise, stress management, and sleep strategies—designed to relieve your symptoms and optimize your health.
During Treatment
Your treatment ships straight to your door. Since everyone metabolizes medications differently, your Hone care team stays with you every step of the way—ready to answer questions and fine-tune your plan so you feel your absolute best.
Membership & Pricing
Hone offers two memberships:
Basic – $25/month for discounted access to a limited number of medications that don’t require lab testing.
Premium – $149/month for everything Hone offers: regular lab testing, physician consults, and full access to our medications.
No commitments. Cancel anytime.