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Home Menopause Care Estrace® Estradiol Cream

Estrace® Estradiol Cream

$40/mo + membership

Delivering estradiol in the form of a vaginal cream, Estrace® effectively alleviates menopause symptoms like vaginal dryness and urinary tract infections while supporting overall vaginal health.

Restore Vaginal Health

Relieve Dryness and Discomfort

Premium Tier

Relieve Menopause Symptoms

  • Improves metabolism
  • Enhances cognitive function
  • Improves metabolic rate
  • Enhances mental clarity
  • Improves mood
  • May reduce risk of osteoporosis

What is Estrace® Estradiol Cream Prescribed For?

Women are prescribed estradiol vaginal cream to help reduce menopause symptoms such as vaginal dryness and urinary tract infections. The hormones in estradiol cream support overall vaginal health.

How Does Estadiol Cream Work?

Gently insert the applicator into your vagina and press the plunger downward to release the cream.

What to Expect

Vaginal estrogen is used to treat vaginal dryness, itching, and burning; painful or difficult urination; and sudden need to urinate immediately in women who are experiencing or have experienced menopause (change of life; the end of monthly menstrual periods).

Learn More About Estrace® Estradiol Cream

Contraindications

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital.

Possible Side Effects

Application site irritation, Breast tenderness, Nausea, Headache, Mood changes

Warnings

Consult with your physician as this prescription may have reactions with other medications.

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Patients see an improvement in quality of life measures in 6 months such as having more energy, improved libido, and increase in strength.

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Patients see their mood improve as measured by the PHQ9 (depressive symptom index) after 6 months of treatment.

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Patients are still with Hone after 1 year of treatment. That's among the highest in health care.

Get Your Consultation for Medications

Get our biomarker test and create a customized health plan with your wholistic health goals in mind.

Biomarker Test

Includes:

Optimal Health Biomarker Test

  • 40+ biomarkers
  • Test at 2,000+ lab locations
  • FSA/HSA eligible

$165 $65

Physician Consultation

  • Private 1:1 video consultation
  • Board-certified experts

Included

Personalized Treatment Plan

  • Comprehensive test results
  • Biomarker breakdown
  • Tailored prescriptions

Included

Subtotal: $165 $65

Explore Treatment Options

Relieve Menopause Symptoms

Testosterone (Cream)

Topical testosterone cream is a treatment option for symptoms related to menopause and testosterone deficiency, and can help to overcome decreased libido, fatigue and mood changes.

Relieve Menopause Symptoms

Estradiol Patch

Estradiol patches can help alleviate symptoms of menopause, including hot flashes, vaginal dryness, and osteoporosis, by supplementing reduced estrogen levels.

Relieve Menopause Symptoms

Bi-est cream

Hone’s Bi-est Cream is available as a 50/50 or 80/20 compound of estradiol and estriol, and is used as a topical treatment to balance hormones and alleviate menopausal symptoms like hot flashes and night sweats.

Relieve Menopause Symptoms

Progesterone

Prescription progesterone tablets help balance and regulate the body’s natural hormone levels to benefit women undergoing menopause or experiencing menstrual conditions.

Relieve Menopause Symptoms

Testosterone (Injections)

In women, testosterone injections are intended to help with symptoms of menopause such as decreased libido, bone loss, and irregular periods.

Testosterone (Cream)
Estradiol Patch
Bi-est cream
Progesterone
Testosterone

Real People. Real Stories.

Story No. 444

Jarred, 42*

I'd say the biggest impacts have been the consistency in my energy levels throughout the day.

Story No. 111

Shannon, 38*

With Hone, I was able to get first class care from a doctor I chose. She was informed about the intersection of chronic illness and reproductive health, and had a plan made up for me quickly that addressed all my concerns.

Story No. 194

Josh, 37*

Very comprehensive review of my blood test and results along with some very helpful suggestions on things I needed to do to address some of the numbers. Didn’t try to sell me on anything, just honest diagnosis.

Story No. 132

Dom, 41*

I have definitely have improved energy, I have less overall pain, and then of course, sexually, it's been good.

Story No. 1947

Dustin, 52*

The benefits have been more than just physical- I 'feel' better in my head. I am clearer and feel confident about myself beyond appearance.

Story No. 732

Polly, 44*

I feel really well supported by the Hone doctor, and my problem of fatigue was solved almost within two weeks of meeting with her.

Story No. 444

Jarred, 42*

I'd say the biggest impacts have been the consistency in my energy levels throughout the day.

Story No. 111

Shannon, 38*

With Hone, I was able to get first class care from a doctor I chose. She was informed about the intersection of chronic illness and reproductive health, and had a plan made up for me quickly that addressed all my concerns.

Story No. 194

Josh, 37*

Very comprehensive review of my blood test and results along with some very helpful suggestions on things I needed to do to address some of the numbers. Didn’t try to sell me on anything, just honest diagnosis.

Story No. 132

Dom, 41*

I have definitely have improved energy, I have less overall pain, and then of course, sexually, it's been good.

Story No. 1947

Dustin, 52*

The benefits have been more than just physical- I 'feel' better in my head. I am clearer and feel confident about myself beyond appearance.

Story No. 732

Polly, 44*

I feel really well supported by the Hone doctor, and my problem of fatigue was solved almost within two weeks of meeting with her.

* Compensated Hone Patient

Start with a deeper look at your health

Identifying your unique needs begins with analysis, including in-depth, 50-biomarker blood testing, personal health history, and validated questionnaires.

$65 per Biomarker Test

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Any Questions?
We’ve got answers.

Getting Started

Hone is  a comprehensive longevity platform that fixes symptoms and optimizes your life to increase your healthspan. Getting started is easy: purchase advanced lab diagnostics for $65, complete your testing either at-home or at-lab, and then meet with your licensed physician.

Consult & Plan

During your private, telehealth consult, a Hone-affiliated licensed physician will dive deep into your personal and family history, review your labs, and pinpoint the root cause of your symptoms. You’ll walk away with a personalized plan—including medications, supplements, diet, exercise, stress management, and sleep strategies—designed to relieve your symptoms and optimize your health.

During Treatment

Your treatment ships straight to your door. Since everyone metabolizes medications differently, your Hone care team stays with you every step of the way—ready to answer questions and fine-tune your plan so you feel your absolute best.

Membership & Pricing

Hone offers two memberships:

Basic – $25/month for advanced lab testing every 6 months, the ability to purchase physician consults, and members-only pricing on select medications and supplements.

Premium – $149/month for everything Hone offers: regular lab testing, physician consults, and full access to our medications.

No commitments. Cancel anytime.