Estriol Cream
$58/mo + membership
Cream containing Estriol, a form of the hormone estrogen that’s considered gentler than estradiol, can be directly applied to relieve symptoms associated with menopause and make sex more comfortable.
Support Hormonal Balance
Relieve Menopausal Symptoms
Premium Tier
Prescription products require an online consultation with a healthcare provider who will determine if a prescription is appropriate.
Relieve Menopause Symptoms
- Alleviates vaginal dryness
- Improves comfort during sex
- Supports overall vaginal health
- Reduces risk of urinary tract infections
What is Estriol Cream Prescribed For?
Estriol cream is a hormone replacement therapy (HRT) that contains estriol, a form of estrogen. It’s used primarily to alleviate menopausal symptoms in the vagina, such as dryness, irritation, and discomfort during sexual intercourse, due to decreased estrogen levels.
How Does Estriol Cream Work?
Estriol cream is applied directly to the vagina, where it replaces estrogen that’s no longer being produced by the ovaries after menopause. This local application helps minimize symptoms by restoring the normal condition of the vaginal tissues.
What to Expect
Clinical evidence shows that Estriol cream can lead to significant improvements in symptoms of urinary incontinence, vaginal lubrication, and pain during intercourse.
Learn More About Estriol Cream
Contraindications
- Unusual vaginal bleeding
- History of or current estrogen-dependent cancers
- History of blood clots or thromboembolic disorders
- Liver dysfunction
- Known or suspected pregnancy
Possible Side Effects
Possible side effects can include local irritation, vaginal discharge, blood clots, and unexpected vaginal bleeding.
Warnings
Do not use this medicine: If you have or have ever had breast cancer, or if you are suspected of having it. If you have cancer which is sensitive to estrogens, such as cancer of the womb lining (endometrium), or if you are suspected of having it. If you have any unexplained vaginal bleeding.
Patients see an improvement in quality of life measures in 6 months such as having more energy, improved libido, and increase in strength.
Patients see their mood improve as measured by the PHQ9 (depressive symptom index) after 6 months of treatment.
Patients are still with Hone after 1 year of treatment. That's among the highest in health care.
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Identifying your unique needs begins with analysis, including in-depth, 50-biomarker blood testing, personal health history, and validated questionnaires.
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Getting Started
Hone is a comprehensive longevity platform that fixes symptoms and optimizes your life to increase your healthspan. Getting started is easy: purchase advanced lab diagnostics for $65, complete your testing either at-home or at-lab, and then meet with your licensed physician.
Consult & Plan
During your private, telehealth consult, a Hone-affiliated licensed physician will dive deep into your personal and family history, review your labs, and pinpoint the root cause of your symptoms. You’ll walk away with a personalized plan—including medications, supplements, diet, exercise, stress management, and sleep strategies—designed to relieve your symptoms and optimize your health.
During Treatment
Your treatment ships straight to your door. Since everyone metabolizes medications differently, your Hone care team stays with you every step of the way—ready to answer questions and fine-tune your plan so you feel your absolute best.
Membership & Pricing
Hone offers two memberships:
Basic – $25/month for advanced lab testing every 6 months, the ability to purchase physician consults, and members-only pricing on select medications and supplements.
Premium – $149/month for everything Hone offers: regular lab testing, physician consults, and full access to our medications.
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