Vagifem®
$65/mo + membership
Vagifem® and Yuvafem are vaginal inserts containing estradiol, an estrogen hormone. Estrogen suppositories are used primarily to treat moderate to severe menopausal symptoms in and around the vagina, such as dryness, itching, and burning.
Vaginal Estrogen Therapy
Target Urogenital Symptoms
Premium Tier
Prescription products require an online consultation with a healthcare provider who will determine if a prescription is appropriate.
Relieve Menopause Symptoms
- Alleviates vaginal dryness
- Improves comfort during sexual intercourse
- Supports overall vaginal health
- Reduces risk of urinary tract infections
What is Vagifem® Prescribed For?
Vagifem® and Yuvafem are vaginal inserts containing estradiol, an estrogen hormone. Estrogen suppositories are used primarily to treat moderate to severe menopausal symptoms in and around the vagina, such as dryness, itching, and burning.
How Do Estrogen Suppositories Work?
Vagifem® and Yuvafem release estradiol directly into the vaginal tissue, where it helps replenish estrogen levels. This local application aids in reducing menopausal symptoms by restoring the health of vaginal tissues and maintaining proper moisture levels.
What to Expect
Results from using Vagifem® or Yuvafem may not be immediate, but significant improvements in symptoms can typically be noticed within 12 weeks. Continuous use of the estrogen suppository as directed can maintain symptom relief and improve the quality of life.
Learn More About Vagifem®
Contraindications
- Unusual vaginal bleeding
- History of or current estrogen-dependent cancers
- History of blood clots or thromboembolic disorders
- Liver dysfunction
- Known or suspected pregnancy
Possible Side Effects
- Trouble sleeping (insomnia)
- Depression
- Vaginal discharge
Warnings
- Possible risk of endometrial cancer
- Potential increased risk of cardiovascular events
- Not recommended for use in individuals with estrogen-dependent neoplasia
- Avoid use in pregnant women
Patients see an improvement in quality of life measures in 6 months such as having more energy, improved libido, and increase in strength.
Patients see their mood improve as measured by the PHQ9 (depressive symptom index) after 6 months of treatment.
Patients are still with Hone after 1 year of treatment. That's among the highest in health care.
Get Your Consultation for Medications
Biomarker Test
Optimal Health Biomarker Test
- 40+ biomarkers
- Test at 2,000+ lab locations
- FSA/HSA eligible
$165 $65
Physician Consultation
- Private 1:1 video consultation
- Board-certified experts
Included
Personalized Treatment Plan
- Comprehensive test results
- Biomarker breakdown
- Tailored prescriptions
Included
Explore Treatment Options
Real People. Real Stories.
* Compensated Hone Patient
Start with a deeper look at your health
Identifying your unique needs begins with analysis, including in-depth, 50-biomarker blood testing, personal health history, and validated questionnaires.
$65 per Biomarker Test
Any Questions?
We’ve got answers.
Getting Started
Hone is a comprehensive longevity platform that fixes symptoms and optimizes your life to increase your healthspan. Getting started is easy: purchase advanced lab diagnostics for $65, complete your testing either at-home or at-lab, and then meet with your licensed physician.
Consult & Plan
During your private, telehealth consult, a Hone-affiliated licensed physician will dive deep into your personal and family history, review your labs, and pinpoint the root cause of your symptoms. You’ll walk away with a personalized plan—including medications, supplements, diet, exercise, stress management, and sleep strategies—designed to relieve your symptoms and optimize your health.
During Treatment
Your treatment ships straight to your door. Since everyone metabolizes medications differently, your Hone care team stays with you every step of the way—ready to answer questions and fine-tune your plan so you feel your absolute best.
Membership & Pricing
Hone offers two memberships:
Basic – $25/month for advanced lab testing every 6 months, the ability to purchase physician consults, and members-only pricing on select medications and supplements.
Premium – $149/month for everything Hone offers: regular lab testing, physician consults, and full access to our medications.
No commitments. Cancel anytime.